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Proteochem"s ultrapure, zero-length crosslinker 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl or EDAC-HCl) is used to conjugate carboxyl functional groups to primary amines as found in peptides and proteins. It is ideal for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticals. EDC-HCl is water soluble, thus the reaction can take place at physiological conditions; although the best results take place at pH of 5.5 or less buffered in MES. Sulfo-NHS or NHS is used as a catalyst for EDC-HCl coupling and greatly increases the efficiency of the reaction.
SpecificationsPurity: ≥ 99%Visual: White powderMelting Point: 110-114ºCClick here for: EDC-HCl Protocol & Product Information Sheet
CAS Number: 25952-53-8Chemical Formula: C8H17N3 · HClMolecular Weight: 191.7EC Number: 247-361-2Beilstein Registry Number:5764110MDL number: MFCD00012503PubChem Substance ID: 24894654Alternative Names: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide HCl; N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride; EDAC.HCl; EDC.HCl Special bulk pricing is available on bulk quantities of EDC for your large volume manufacturing application.