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EDC-HCl zero-length crosslinker (EDAC-HCl, EDC or EDAC; EDCI; 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride) from ProteoChem is ultrapure, and is used to conjugate carboxyl functional groups to primary amines as found in peptides and proteins. It is ideal for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticals. The convenient 10 mg packaging isgreat for using ProteoChem"s EDC-HCl in Luminex bead conjugation reactions.EDC-HCl is water soluble, thus the reaction can take place at physiological conditions; although the best results take place at pH of 5.5 or less buffered in MES. Sulfo-NHS or NHS is used as a catalyst for EDC-HCl coupling and greatly increases the efficiency of the reaction.
SpecificationsPurity: ≥ 99%Visual: White powderMelting Point: 110-114ºCClick here for: EDC-HCl Protocol & Product Information Sheet
CAS Number: 25952-53-8Chemical Formula: C8H17N3 · HClMolecular Weight: 191.7EC Number: 247-361-2Beilstein Registry Number:5764110MDL number: MFCD00012503PubChem Substance ID: 24894654Alternative Names: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide HCl; N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride; EDAC.HCl; EDC.HCl; EDCIReferences:Bastarrachea, L. J., Peleg, M., McLandsborough, L. A., & Goddard, J. M. (2013). Inactivation of< i> Listeria monocytogenes on a polyethylene surface modified by layer-by-layer deposition of the antimicrobial N-halamine. Journal of Food Engineering.Bastarrachea, L. J., & Goddard, J. M. (2013). Development of antimicrobial stainless steel via surface modification with N‐halamines: Characterization of surface chemistry and N‐halamine chlorination. Journal of Applied Polymer Science, 127(1), 821-831.Special bulk pricing is available on bulk quantities of EDC-HCl for your large volume manufacturing application.